US 421 Traffic

• US Route 421 Accident Reports
• US Route 421 Weather Conditions

Live Reports from the DOT's Twitter

• 2 days ago

  TrafficWise

  US 421 NB/SB: Road cleared between Alan John Dr and IN 2 (MM 222.7, Westville). https://t.co/MqmYWy696C

• 2 days ago

  TrafficWise

  US 421 NB/SB: Crash between Alan John Dr and IN 2 (MM 222.7, Westville). https://t.co/MqmYWy5Bh4

DOT Accident and Construction Reports

• Accident on Old US 421 from Post Rd/Exit 96 (I-74) to I-465/Exit 94B (I-74).

  TYPE: Accident Serious

US 421 News Reports

• Harlan County honors late Senator Johnnie L. Turner

  • Kentucky
  • Harlan
  • US 421

  • source: Bing
  • 5 views
  • Dec 16, 2025 5:37pm
  421

  HARLAN CO., Ky. (WYMT) - A section of a highway in Harlan County will honor the memory of late Senator Johnnie L. Turner. During a Harlan Co. Fiscal Court meeting, officials presented the Turner ... Read More

• Woman dies in wrong-way crash on US 421 in Wilkes County, troopers say

  • North Carolina
  • Us421

  • source: Bing
  • 27 views
  • Dec 05, 2025 06:53am
  WILKESBORO, N.C. (WGHP) - A woman was killed and another person was injured in a wrong-way crash Thursday, according to the North Carolina State Highway Patrol. At 11:50 p.m., the NCSHP responded to a ... Read More

• Wrong-way crash on US 421 claims life of 76-year-old woman in Wilkes County

  • North Carolina
  • Accident

  • source: Bing
  • 24 views
  • Dec 05, 2025 06:38am
  On Dec. 4 at approximately 11:50 p.m., the North Carolina State Highway Patrol responded to a fatal collision on US 421 in Wilkes County.A 2014 Ford Taurus, dr ... Read More

• 76-year-old woman killed in wrong-way crash on US 421 in Wilkes Co.

  • North Carolina
  • Us421

  • source: Bing
  • 25 views
  • Dec 05, 2025 05:15am
  A 76-year-old woman was killed in a wrong-way car crash in Wilkes County. The North Carolina State Highway Patrol said the crash occurred on Thursday just before midnight on U.S. 421. Troopers said ... Read More

• 21-year-old woman fatally injured in US 421 crash

  • Indiana
  • Old US 421

  • source: Bing
  • 30 views
  • Nov 29, 2025 5:17pm
  A 21-year-old woman was fatally injured in a crash on U.S. 421 Saturday, according to the Boone County Sheriff's Office. At 5:09 p.m. Saturday, Boone County deputies responded to a single-vehicle ... Read More

• US 421 temporarily closed

  • Indiana
  • N US Highway 421

  • source: Bing
  • 12 views
  • Dec 15, 2025 07:02am
  As of 11:02 a.m. Monday, Dec. 15, a stretch of U.S. Hwy. 421 approximately 3 miles north of Napoleon was closed as the result of a semi rollover earlier in ... Read More

• Shots fired in crash on US 421 in Kernersville; 19-year-old charged

  • North Carolina
  • Nc 421

  • source: Bing
  • 11 views
  • Dec 01, 2025 04:29am
  A 19-year-old is facing charges after being accused of shooting a gun following a crash on US 421 in Kernersville, according to the Kernersville Police Department. At ... Read More