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Current Route 378 Traffic Conditions
Route 378 Traffic Delays
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Mississippi Route 378
250mi From to
4 hours 6 mins travel time instead of 3 hours 41 mins
25 minutes Delay
Route 378 News Reports
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1 dead, 2 hospitalized in Highway 378 head-on crash
- South Carolina
- US 378 Near Conway
- source: Bing
- 6 views
- Mar 23, 2026 03:38am
378 A Highway 378 head-on collision left one person dead and two others hospitalized, according to the South Carolina Highway Patrol. The incident happened just ... Read More
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Crash closes Route 378 in Bethlehem
- Pennsylvania
- Bethlehem
- PA-378
- source: Bing
- 55 views
- Mar 10, 2026 5:22pm
BETHLEHEM, Pa. -- A crash closed Route 378 North in Bethlehem on Tuesday evening. A car flipped and ended up on its side in the grass next to the highway, near Route 22. The driver was rescued from ... Read More
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1 killed, 2 hurt in Florence County wreck near Pee Dee River Bridge
- South Carolina
- Eastbound Highway
- source: Bing
- 61 views
- Feb 22, 2026 3:52pm
FLORENCE COUNTY, S.C. (WBTW) - One person was killed and two others were hurt Saturday afternoon in a wreck along U.S. Route 378 in Florence County. It happened just before 3 p.m. when an SUV ... Read More