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SAFD says that two riders were on a motorcycle when it crashed. When officials arrived one person was dead, and one was critically injured and taken to the hospital. Read More

A crash on the southbound lanes of Highway 281 on the North Side has closed most lanes, according to the Texas Department of Transportation. Read More

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SAN ANTONIO - An accident involving a motorcycle closed down Highway 281 north of downtown Saturday afternoon. It happened just before noon on Highway 281 at Evans Road, heading into town. The road ... Read More

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A crash on the southbound lanes of Highway 281 on the North Side has closed most lanes, according to the Texas Department of Transportation. Read More

Police initially responded for a hit-and-run crash near La Ventana Drive and South US Highway 281 on Wednesday. Read More

The Texas Department of Public Transportation is seeking public feedback on two projects along U.S. Highway 281 in Blanco County. Read More

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A portion of U.S. Highway 281 in northern Osborne County has been closed for reconstruction since late March and was scheduled to be open by the end of November. On Friday, the Kansas Department of ... Read More

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A 31-year-old central Nebraska man Monday after his vehicle rear-ended a semitrailer truck on U.S. Highway 281 ... Read More

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DONIPHAN, Neb. (KSNB) - A Hastings man is dead after a Monday morning crash on Highway 281. The Hall County Sheriff's office said the accident happened about 6:35 a.m. in the north-bound lanes of the ... Read More

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DONIPHAN, Neb. (KSNB) - A crash was reported on Monday morning south of Doniphan shortly after 6:30 a.m. The crash was located near Highway 281 and Binfield Road. Our reporter on scene could see a ... Read More

A motorist died following a two-vehicle collision at the intersection of State Route 281 and Preble Road on Oct. 24. The Cortland County Sheriff's Office responded to the crash at approximately 10:45 ... Read More

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Troopers responded to a three-vehicle crash on Highway 281 near milepost 7 in Hood River County that took the life of Phillip Mickey Himes, 37, of Hood River. OSP's preliminary investigation indicated ... Read More

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KSAT reporter Devan Karp shows a downed power line, which caused the road to be closed at the intersection of U.S. Highway 281 and FM 306 in Comal County. Read More