LADUE, Mo. - Eastbound Interstate 64 Highway 40 has reopened after a pedestrian was struck near Clayton Road in the Ladue area just after 8 p.m. on Tuesday. The incident did not result in a fatality, ... Read More

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The left two lanes on I-64 E in that area are still blocked. Traffic is being directed to the right two lanes. There ... Read More

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ST. LOUIS, Mo. (First Alert 4) - A shooting victim was discovered during a traffic stop in Clayton. On Tuesday, Clayton police said that an officer stopped a vehicle driving erratically on Clayton ... Read More

Two people had to be taken to the hospital following a multi-vehicle traffic crash Monday on Interstate 64 westbound at Illinois 111 near milepost 6 in Washington Park. No immediate medical ... Read More

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A nine-vehicle crash sparked closures of lanes of Interstate 270 near Interstate 64 on Tuesday morning, Aug. 12, 2025.The Missouri ... Read More

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Multiple lanes were shut down for an extended period Tuesday morning after reports of a multi-vehicle crash on Interstate 270. The crash took place around 6 a.m. on northbound I-270 before I-64, ... Read More

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ST. LOUIS, Mo. (First Alert 4) - A crash has shut down part of Interstate 270 near Interstate 64. MoDOT says the crash was reported around 6 a.m. in the northbound lanes of I-270. Two left lanes are ... Read More

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ST. LOUIS, Mo. (First Alert 4) - A crash has shut down part of Interstate 270 near Interstate 64. MoDOT says the crash was reported around 6 a.m. in the northbound lanes of I-270. Two left lanes are ... Read More

The Winchester Police Department reports that the Mountain Parkway is closed eastbound from I-64 to exit 10 due to an overturned cattle trailer on Wednesday morning. Read More

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The Missouri Department of Transportation (MoDOT) will shift traffic on Boone Bridge on westbound Interstate 64 starting at 7 p.m. on Wednesday, Aug. 6 as part of its rehabilitation project ... Read More