LADUE, Mo. - Eastbound Interstate 64 Highway 40 has reopened after a pedestrian was struck near Clayton Road in the Ladue area just after 8 p.m. on Tuesday. The incident did not result in a fatality, ... Read More

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ST. LOUIS, Mo. (First Alert 4) - A shooting victim was discovered during a traffic stop in Clayton. On Tuesday, Clayton police said that an officer stopped a vehicle driving erratically on Clayton ... Read More

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An investigation is underway after someone shot at a car on Interstate 64 overnight, injuring two people inside. Read More

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According to Clayton Police Chief Mark Smith, officers pulled over a car on Clayton Road for erratic driving. When police spoke with the people inside the car, they told the officer that one of the ... Read More

Two people had to be taken to the hospital following a multi-vehicle traffic crash Monday on Interstate 64 westbound at Illinois 111 near milepost 6 in Washington Park. No immediate medical ... Read More

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A nine-vehicle crash sparked closures of lanes of Interstate 270 near Interstate 64 on Tuesday morning, Aug. 12, 2025.The Missouri ... Read More

The Winchester Police Department reports that the Mountain Parkway is closed eastbound from I-64 to exit 10 due to an overturned cattle trailer on Wednesday morning. Read More